Paola C. Rosas

My research aims to study the pathways that lead to heart failure due to stressors such as aging, obesity, and diabetes with special focus on heart failure with preserved ejection fraction (HFpEF). I also investigate the underlying mechanisms of sex differences in the incidence of heart failure. Methods include echocardiography, intra-cardiac pressure-volume measurements, simultaneous force and intracellular calcium measurements on intact papillary muscles, biochemistry techniques, phosphorylation techniques, and molecular biology techniques.